薬学の世界

18 Labs

体内での薬の運命 薬物動態解析学研究室

【学会発表】 2015年以降

日本薬剤学会 第31年会 2016

Glycerol誘発性腎障害ラットにおけるMRPs基質の赤血球内蓄積 –各種尿毒症物質の影響解析-

松島 葵、小田 啓祐、中元 祐太、森 信博、村上 照夫

 

日本薬学会 第136年会 2016

難水溶性薬物の溶解・消化管吸収に及ぼす両親媒性包接化合物サイクリックビスデスモシドの影響

小田 啓祐、森 信博、猪山 陽輔、村上 照夫

 

日本薬物動態学会 第30年会 2015

Accumulation of DNP-SG in erythrocyte after administration of CDNB in glycerol-induced acute renal failure rats.

Aoi Matsushima, Keisuke Oda, Nobuhiro Mori, Teruo Murakami

 

日本薬剤学会 第30年会 2015

ABCトランスポーター基質の消化管吸収に及ぼすポリフェノール含有飲料水の影響

小田 啓祐、金城 拓也、石岡 朋子、山田 千晴、森 信博、村上 照夫

 

【学術論文】 2012年以降

Yokooji T, Kameda Y, Utsumi M, Mori N, Murakami T.
Interaction of hydrophobic components in female urine before and after childbirth with P-glycoprotein in vitro. Pharmazie 69: 430-43, 2014.

Yamasaki M, Funakoshi S, Matsuda S, Imazu T, Takeda Y, Murakami T, Maeda Y.
Interaction of magnesium oxide with gastric acid secretion inhibitors in clinical pharmacotherapy. Eur J Clin Pharmacol. 70(8):921-924, 2014.

Yokooji T, Kawabe Y, Mori N, Murakami T.
Effect of genistein, a natural soy isoflavone, on the pharmacokinetics and intestinal toxicity of irinotecan hydrochloride in rats. J Pharm Pharmacol. 65: 280-291, 2013.

Takano M, Yamamoto C, Sambuichi K, Oda K, Nagai J, Shimamoto A, Tahara H, Yumoto R.
Introduction of a single transporter gene ABCA3 directs RLE-6TN to more type-II like alveolar epithelial cells. Membrane. 38(5):246-53, 2013.

Oda K, Yumoto R, Nagai J, Takano M.
Modulation of insulin transport by D-glucose in alveolar epithelial cells. Biomedicine & Aging Pathology. 3(4):247-52, 2013.

Oda K, Yumoto R, Nagai J, Katayama H, Takano M.
Enhancement effect of poly(amino acid)s on insulin uptake in alveolar epithelial cells. Drug Metabolism and Pharmacokinetics. 27(6):570-8, 2012.

Yumoto R, Suzuka S, Oda K, Nagai J, Takano M.
Endocytic uptake of FITC-albumin by human alveolar epithelial cell line A549. Drug Metabolism and Pharmacokinetics. 27(3):336-43, 2012.

Hirose K, Kozu C, Yamashita K, Maruo E, Kitamura M, Hasegawa J, Omoda K, Murakami T, and Maeda Y.
Relationship between concentration ratios of SN-38 glucuronide against SN-38 in plasma and neutropenia induction in Japanese patients with colorectal cancer and wild-type UGT1A1 gene. Oncology Letters. 3: 694-698, 2012.

Murakami T, Mori N,
Involvement of multiple transporters-mediated transports in mizoribine and methotrexate pharmacokinetics.
Pharmaceuticals 5: 802-836, 2012.

Mori N, Yamamoto M, Tsukada E, Yokooji T, Matsumura N, Sasaki M, Murakami T.
Comparison of in vivo with in vitro pharmacokinetics of mercury between methylmercury chloride and methylmercury cysteine using rats and Caco2 cells. Arch Environ Contam Toxicol. 63: 628- 636, 2012.

Mori N, Iwamoto H, Yokooji T, Murakami T.
Characterization of intestinal absorption of quinidine, a P-glycoprotein substrate, given as a powder in rats. Pharmazie. 67: 384-388 2012.

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