薬学の世界

18 Labs

薬の効き方 神経薬理学研究室

[学会発表]

第46回日本神経精神薬理学会年会(2016年7月)
モルヒネによる条件付け場所嗜好性に対する抗うつ薬の効果
石原 熊寿、大山 飛鳥、伊東 真理

第89回日本薬理学会年会(2016年3月)
リポポリサッカライドにより活性化されたマクロファージのシグナル伝達に及ぼすポリリン酸の影響
原田 佳奈、仲谷 翼、三木 直樹、石原 熊寿

日本脳神経外科学会第74回学術総会(2015年10月)
Noda epileptic rat (NER) のてんかん発作に対する迷走神経刺激による発作抑制効果
片桐 匡弥、石原 熊寿、飯田 幸治、香川 浩太、橋詰 顕、原田 佳奈、庫本 高志、栗栖 薫

第48回日本てんかん学会学術集会(2014年10月)
迷走神経刺激ラット視床における神経活動の免疫組織化学的検討
片桐 匡弥、石原 熊寿、飯田 幸治、香川 浩太、橋詰 顕、原田 佳奈、大野 行弘、栗栖 薫

第87回日本薬理学会年会(2014年3月)
メタンフェタミンによる条件付け場所嗜好性に対する抗うつ薬の効果
石原 熊寿、田北 麻衣

第87回日本薬理学会年会(2014年3月)
強制水泳が海馬FGF20量および無動時間に与える影響
小田 徹、石原 熊寿

[発表論文]

The Toll-like receptor 4-activated neuroprotective microglia subpopulation survives via granulocyte macrophage colony-stimulating factor and JAK2/STAT5 signaling
Mayumi Kamigaki, Izumi Hide, Yuhki Yanase, Hiroko Shiraki, Kana Harada, Yoshiki Tanaka, Takahiro Seki, Toshihiko Shirafuji, Shigeru Tanaka, Michihiro Hide, Norio Sakai
Neurochem. Int. 93, 82—94 (2016)

Serotonergic modulation of neuronal activity in the nucleus accumbens following repeated methamphetamine administration in rats
Kumatoshi Ishihara, Naomichi Takahashi, Naoki Komoto, Chisato Yoshikawa, Shuhei Fukumoto, Soichiro Ide, Takeshi Kimura, Koichiro Ozawa
Journal of Pharmacological Sciences 123, 140—146 (2013)

Inorganic polyphosphate suppresses lipopolysaccharide-induced inducible nitric oxide synthase (iNOS) expression in macrophages
Kana Harada, Toshikazu Shiba, Kazuya Doi, Koji Morita, Takayasu Kubo, Yusuke Makihara, Adriano Piattelli, Yasumasa Akagawa
PLOS ONE 8, e74650 (2013)

Inhibitory effects of levetiracetam on the high-voltage-activated L-type Ca²⁺ channels in hippocampal CA3 neurons of spontaneously epileptic rat (SER)
Hai-Dun Yan, Kumatoshi Ishihara, Takahiro Seki, Ryosuke Hanaya, Kaoru Kurisu, Kazunori Arita, Tadao Serikawa, Masashi Sasa
Brain Res. Bull. 90, 142—148 (2013)

Na+/Ca2+ exchanger inhibitors inhibit neurite outgrowth in PC12 cells
Toru Oda, Toshiaki Kume, Yasuhiko Izumi, Kumatoshi Ishihara, Hachiro Sugmimoto, Akinori Akaike
J. Pharmacol. Sci. 116, 128—131 (2011)

Antidepressant-like effect of venlafaxine is abolished in μ-opioid receptor-knockout mice
Soichiro Ide, Shunsuke Fujiwara, Masayuki Fujiwara, Ichiro Sora, Kazutaka Ikeda, Masabumi Minami, George R. Uhl, Kumatoshi Ishihara
J. Pharmacol. Sci. 114, 107—110 (2010)

Reduced emotional and corticosterone responses to stress in mu-opioid receptor knockout mice
Soichiro Ide, Ichiro Sora, Kazutaka Ikeda, Masabumi Minami, George R. Uhl, Kumatoshi Ishihara
Neuropharmacology 58, 241—247 (2010)

Abolished thermal and mechanical antinociception but retained visceral chemical antinociception induced by butorphanol in mu-opioid receptor knockout mice
Soichiro Ide, Masabumi Minami, Kumatoshi Ishihara, George R. Uhl, Masamichi Satoh, Ichiro Sora, Kazutaka Ikeda
Neuropharmacology 54, 1182—1188 (2008)

Voltage-dependent calcium channel abnormalities in hippocampal CA3 neurons of spontaneously epileptic rats
Hai-Dun Yan, Kumatoshi Ishihara, Ryosuke Hanaya, Kaoru Kurisu, Tadao Serikawa, Masashi Sasa
Epilepsia 48, 758—764 (2007)

Mu opioid receptor-dependent and independent components in effects of tramadol
Soichiro Ide, Masabumi Minami, Kumatoshi Ishihara, George R. Uhl, Ichiro Sora, Kazutaka Ikeda
Neuropharmacology 51, 651—658 (2006)

Long-lasting antiepileptic effects of levetiracetam against epileptic seizures in the spontaneously epileptic rat (SER): differentiation of levetiracetam from conventional antiepileptic drugs
Cai Ji-qun, Kumatoshi Ishihara, Takashi Nagayama, Tadao Serikawa, Masashi Sasa
Epilepsia 46, 1362—1370 (2005)

Separation of antiepileptogenic and antiseizure effects of levetiracetam in the spontaneously epileptic rat (SER)
Hai-Dun Yan, Cai Ji-qun, Kumatoshi Ishihara, Takashi Nagayama, Tadao Serikawa, Masashi Sasa
Epilepsia 46, 1170—1177 (2005)

Augmentation of serotonin-induced inhibition of neuronal activity in the hippocampus following repeated treatment with methamphetamine
Takeshi Kimura, Kumatoshi Ishihara, Koichiro Ozawa, Masashi Sasa
Ann. N. Y. Acad. Sci. 1025, 242—247 (2004)

Failure of repeated electroconvulsive shock treatment on 5-HT4-receptor-mediated depolarization due to protein kinase A system in young rat hippocampal CA1 neurons
Kumatoshi Ishihara, Masashi Sasa
J. Pharmacol. Sci. 95, 329—334 (2004)
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